New vaccine technique targets multiple poultry diseases

The Pirbright Institute
March 01, 2018
By The Pirbright Institute
Researchers at The Pirbright Institute have created a new method of genetically modifying the Marek’s disease vaccine so that it is able to protect against another destructive poultry virus called infectious bursal disease (IBD), and potentially others such as avian influenza and Newcastle disease. This approach could lead to a reduction in the number of vaccines that need to be administered to each bird.

For the first time, Pirbright scientists have been able to use a gene editing system called CRISPR/cas9 to add a gene of the IBD virus into a current Marek’s disease vaccine virus. The added genetic material protects poultry against IBD in addition to the protection already offered by the Marek’s disease vaccine, meaning that bird owners would only need to use one vaccine instead of two. For the full story, click here.

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