The objectives of the program are as follows:
- to encourage and support graduate students to carry out poultry science research
- to build Canada’s intellectual capacity in poultry science
- to promote graduate research in poultry science at Canadian universities
To be eligible for a CPRC scholarship award, a student must be studying (or planning to study) an aspect of poultry science. Applicants are assessed on a number of criteria, including academic performance, research aptitude, career goals and a demonstrated interest in poultry research.
A postgraduate scholarship supplement is available to students who hold a Natural Sciences and Engineering Research Council (NSERC) scholarship. Several excellent students have received supplements to their scholarships through this program since its inception in 2006, and as of 2011, the CPRC scholarship is also available to non-NSERC scholars. This change broadened the availability of the scholarship program to accommodate more students with an interest in poultry science.
Applications to either the scholarship or supplement are due May 1 of each year. Only one award of $7,500 is given out per year and it is available to master’s (eligible for one year) or doctoral level (eligible for up to two years) students.
Details of the program, including the application requirements and the past winners, are available on the “Scholarship” section of the CPRC website (www.cp-rc.ca).
And the winner is…
The 2013 CPRC scholarship was awarded to Kayla Price, a PhD student studying under John Barta at the University of Guelph. She is studying Eimeria, the causative organism of coccidiosis in poultry, and looking at practical ways to improve its control in commercial pullets reared on wire floors.
Price’s research has demonstrated the effectiveness of a self-immunization strategy that improves the performance of live cocci vaccines and may reduce the need for coccidiostats, about which there is growing concern over resistance and residues. She has also expanded her original research program to better understand the dynamics of coccidial populations in the bird and in the barn, and to optimize live vaccine doses.
Price has had a very successful academic career thus far, having already published several papers in peer-reviewed journal articles and presented her results at a number of scientific and industry meetings in Canada and abroad. She has received several awards in recognition of her outstanding academic performance.
Beyond academics, Price is highly involved in several activities, both in and outside the university community, aimed at transferring knowledge to potential users of research outcomes, encouraging others to become involved in poultry science and promoting the poultry industry in general.
Price has already made significant contributions to her research program and displays great potential to mature into a scientist of excellent calibre – the kind of scientist we need to help ensure the future success of our industry.
The membership of the CPRC consists of Chicken Farmers of Canada, Canadian Hatching Egg Producers, Turkey Farmers of Canada, Egg Farmers of Canada and the Canadian Poultry and Egg Processors’ Council. CPRC’s mission is to address its members’ needs through dynamic leadership in the creation and implementation of programs for poultry research in Canada, which may also include societal concerns.
Sept. 12, 2013, Ottawa, ON - As wild birds begin their fall migration, Canada's ninth annual Inter-Agency Wild Bird Influenza Survey is underway. The survey is part of global efforts advocated by the World Organisation for Animal Health (OIE) and the Food and Agriculture Organization of the United Nations (FAO) to detect avian influenza viruses that could threaten the agricultural sector and human health.
Canada's wild bird survey is coordinated by the Canadian Cooperative Wildlife Health Centre on behalf of the Canadian Food Inspection Agency (CFIA), the Public Health Agency of Canada, and Environment Canada, as well as provincial and territorial government partners. The survey will have an increased sample size this year, as part of efforts to look for the potential presence of significant influenza viruses and indications of viruses from Europe and Asia.
The survey includes testing live and dead wild birds. Live birds are tested in order to track the viruses circulating in the wild bird population, as well as the genetic changes and exchanges that occur in these viruses over multiple years. Dead birds are tested in order to detect potential presence of highly pathogenic influenza viruses in the wild. The 2013-2014 survey will try to sample approximately 1,500 dead birds and between 1,000 and 2,000 live birds across Canada.
Anyone who finds a dead wild bird should contact the Canadian Cooperative Wildlife Health Centre at 1-866-544-4744 or visit www.ccwhc.ca.
If the survey were to detect a virus of concern in wild birds in a location close to a poultry flock, the CFIA would alert producers in the area and conduct heightened surveillance in domestic poultry. The CFIA routinely monitors for notifiable avian influenza viruses in commercial flocks.
The CFIA is reminding producers and backyard flock owners of the importance of practicing biosecurity in order to protect their flocks from diseases such as avian influenza and Newcastle disease.
The following key biosecurity measures can help protect poultry health:
- Do not allow poultry or their feed and water to have contact with wild birds -- particularly ducks and other wild waterfowl, which are known to be reservoirs for avian influenza viruses.
- Control movements of people, animals, equipment and vehicles on your property.
- Observe your animals daily for signs of disease.
For more information on the measures you can take to protect your poultry from diseases, visit www.inspection.gc.ca/biosecurity.
The donation from James and Brenda McIntosh, owners of McIntosh Poultry Farms Ltd. in Seaforth, Ont., will establish a new professorship through the Department of Animal and Poultry Science in the Ontario Agricultural College (OAC).
The gift was made as part of the University's BetterPlanet Project, a $200-million fundraising campaign to help improve the quality of food, environment, health and communities here and around the world.
The new investment will pay for the McIntosh Family Professorship in Poultry Nutrition for 10 years; the college will then provide base funding for this permanent position.
“James and Brenda McIntosh are long-time friends and supporters of our institution and passionate about agriculture and food production,” said OAC dean Robert Gordon. “Thanks to their commitment and generosity, Guelph will remain a leader in poultry research and education globally. Through their gift, we will be able to continue to develop the next generation of leaders for this important and evolving industry.”
James McIntosh earned an undergraduate degree from OAC in 1959 and a master’s degree in poultry nutrition in 1961. “My years at the University were enjoyable, both as a time to learn and as a time to make lifelong friendships,” he said.
"The OAC is where I met Brenda, my wife and business partner, and the friendships I developed proved invaluable in my career in agriculture. Plus, being a graduate of OAC provided an immediate introduction and connection to others in the agriculture industry who graduated from the same school."
The professorship is expected to be filled in 2014. Gordon said it represents a significant step toward boosting the college’s impact on the industry, nationally and globally. “This leadership gift will help us maintain essential teaching and extension capacity that is relevant to the needs of the industry today and vital for the creation of opportunities for the future.”
The research focus of the professorship will address current industry priorities and issues, Gordon added.
For example, feed still represents the major cost of production in the Ontario poultry industry. In recent years, there has been a dramatic increase in the price of feed due to global changes affecting corn, soybean and other ingredients. Relief from input costs is not expected any time soon.
Research focused on digestion of feed and absorption of nutrients will help improve the overall efficiency of poultry production and be of interest to producers, said Gordon. “We see a real need and opportunity to support the industry through recruiting an individual who will bring to the University a commitment to work collaboratively and develop a world-class program to address these research opportunities.”
The award was presented to Synergy Agri production manager Gary McAleer and the production team by Cobb-Vantress technical service manager for Eastern Canada, David Engel, and Canada sales manager Philippe Dufour.
Ranked on adjusted chicks per hen to 65 weeks of age, the company averaged 144.21 chicks per hen housed. "Gary and the team at Synergy have consistently produced great results," said David Engel. "With the number of Cobb parent flocks in Canada steadily increasing, we're very happy to recognize this tremendous achievement."
Gary McAleer thanked the many people involved in gaining the award. He stated: "From the employees who clean barns, egg collectors, caretakers, our transportation team, feed mill employees, office staff to our management team and owners ..... each one of our Synergy team played an important role in realizing our goals which led, in turn, to this award.
"I'd also like to acknowledge the sales and tech team from Cobb-Vantress for their support and guidance over the past several years. To quote Henry Ford: 'Coming together is a beginning. Keeping together is progress. Working together is success.' Thanks to everyone who came together to help us attain our goals."
In this inaugural year for Cobb performance awards in Canada, there was also recognition for the best performing individual flocks for the Cobb 500FF and Cobb 500SF lines, based on ranking using chicks per hen adjusted to 65 weeks of age.
Groupe Westco of St. Francois, New Brunswick, was the winner for the best Cobb 500FF flock. The flock from Barn 303, produced 157.7 chicks/hen housed.
Poirier-Berard of St. Felix-de-Valois, Quebec, was the winner for the best Cobb 500SF flock. The flock from Ferme Martineau — Barn #5, produced 147.55 chicks/hen housed.
Aug. 26, 2013 - Arsenic is a known carcinogen, has been used in insecticides and is a very potent poison. It also has been used as an additive to poultry and swine feed in order to increase weight gain and feed efficiency, as well as an anti-parasitic.
And since arsenic is toxic, public health experts believe that exposure through water and food needs to be controlled and exposure should be minimized as much as possible. However, researchers at the Johns Hopkins Center for a Livable Future at the Bloomberg School of Public Health have found increased levels of arsenic in retail chicken meat from producers who use arsenic-based drugs.
Keeve Nachman, assistant scientist and director of the Farming for the Future Program, says that with all the knowledge regarding arsenic posing a number of adverse health conditions, use of arsenic-based drugs is still perfectly legal. "Despite this, arsenical drug use remains federally-approved in animal production," he said. "This study sought to understand the chemical form of arsenic that remained in chicken meat as a result of arsenical drug use."
The researchers purchased different types of chicken from major metropolitan areas in the U.S. from December 2010 to June 2011. This time frame was used as it coincided with when an arsenic-based drug, roxarsone, was still readily available. They found that chickens likely raised with the drug had four times higher the levels of inorganic arsenic in their meat than those without drugs.
Interestingly, Nachman found that cooking the chicken made the situation worse – not better. "We also found that cooking the chicken increased the fraction of arsenic that was present in the toxic form, and decreased residues of the original, less toxic arsenic-based drug."
Since some arsenic-based drugs (such as nitarsone) are available to producers, Nachman added, their use equates to an unnecessary risk to consumers. The only solution is clear, says Nachman. "Withdrawing these drugs would lower levels of arsenic in chicken and turkey meat, and lower population arsenic exposures."
The poultry industry could never be accused of resting on its laurels. It seems that every day there are new initiatives being undertaken to ensure that poultry producers have access to information, technology and the people who can help their farms remain successful.
Now, you can add one more initiative to the growing list – the University of Guelph’s Poultry Health Research Network (PHRN). Guelph has had a long-standing commitment to animal health, but now, the PHRN aims to further tighten technology transfer and enhance poultry research by creating a network of experts, consisting of poultry researchers and poultry health specialists, who address problems ranging from very basic biological processes to environmental concerns and industry-relevant issues.
Dr. Shayan Sharif is leader of the PHRN, which was established in 2012.
“What we are basically trying to do is to create a network of people, poultry researchers, who can address any sort of problem from basic to a very applied type of research,” he says. “This network is part of an integrated plan within the university and is a priority for both the Ontario Veterinary College and the University of Guelph. We are attempting to solidify the interactions between researchers and departments.”
The network aims to provide a forum for collaboration and co-operation not only among researchers within Guelph, but also between Guelph and other Canadian campuses. It will also, hopefully, reduce duplication where applicable.
While Sharif admits that there are other similar initiatives in Canada, and one in Georgia, he says that Guelph’s is unique because rather than focusing on production, as the name implies, this one focuses on health. But the idea is that all will complement each other.
The roster for the network currently includes 36 names, each one, says Sharif, being a “poultry health researcher and specialist.” Most participants (who could be approached or volunteer to participate) are from Guelph, with department affiliations varying from pathobiology and animal science to food science and mathematics – even engineering.
“Our team member from engineering is looking at the effect of poultry industries on the environment and human health. The computer science department is looking at modelling of poultry diseases, mathematically, but using computer software.”
The consumer studies and geography departments are also looking at the influence of poultry production on livelihoods of people, especially women in developing countries.
“In Africa, for example, women are the ones who look after raising chickens, while men look after raising cattle, and that actually has something to do with their social status,” says Sharif. “So, the researcher’s hypothesis is that by changing the way poultry is raised, you can [increase] social status.”
Within the network there is also a lot of expertise in vaccine development and diagnostic testing. There are also two industry members, Tim Nelson (Livestock Research Innovation Corporation, LRIC) and Brue Roberts (Canadian Poultry Research Council, CPRC). Both organizations fully endorse the initiative, along with the Poultry Industry Council.
The ultimate goal of research programs within the PHRN is to increase poultry health in Canada by facilitation and provision of means for production of safe, healthy and ethically produced poultry and poultry products. A key component is that the network is trying to strengthen interaction with industry, and that is also a top priority for the initiative.
Sharif says another item that’s high the to-do list is to create training programs that will help to qualify personnel for specific tasks. Ideally, he sees opportunities for both students and professionals so that they can become qualified via degree or non-degree programs. OVC has already taken steps toward reaching this goal by providing funding to hire a faculty member in avian diseases and health.
“We have managed to justify the hiring of a faculty person, even in this climate of economic downturn,” muses Sharif. “This person will be able to help with promotion, as well as officially being the avian disease specialist.”
Because the initiative is receiving some funding, the OVC will ensure that the network meets its objectives and remains accountable through a quarterly reporting system that goes directly to the Dean of the OVC, Dr. Elizabeth A. Stone. The network is set up similarly to a board. With Sharif as the leader and coordinator, meetings will be called on a fairly regular basis, given the research work and many hats worn by each of its members. Sharif hopes that they can physically get together at least every three to four months.
The network’s first official meet-and-greet, which took place on July 30, was informal, allowing the participants to become more familiar with one another and their respective research. Sharif says he’s also hoping to hold an industry day to showcase the network. This would be an opportunity for industry stakeholders to interact with members and learn more about what they do, and foster and strengthen interactions with industry.
There are no immediate plans to have the PHRN function as an incorporated organization with brick-and-mortar offices, but Sharif says that is a possibility for the future that obviously would require funding and much support from the industry level to ensure it is warranted.
The PHRN now has a website (www.uoguelph.ca/phrn), and a Twitter account will follow, which will highlight network information, news and events.
It is key not to confuse what the PHRN does with organizations like the Poultry Industry Council (PIC), CPRC or LRIC.
The PIC remains very involved in setting poultry research priorities and in developing and delivering programs that put the research results to work for industry more effectively and efficiently. Its board decides what it will and won’t fund.
CPRC’s mission, on the other hand, is to address national marketing boards and processor needs through the creation and implementation of programs for poultry research in Canada – which may also include societal concerns.
Says Tim Nelson, “LRIC’s mandate is to work on behalf of all livestock and poultry in Ontario to deliver a better return on investment for our research dollars. We also take on the administration of research for the various sectors, creating a simplified ‘one-window’ approach to research management from OMAF’s perspective and the research provider’s perspective (University of Guelph).”
Within the university, it also is important not to confuse the PHRN with the pre-existing Poultry Program Team (PPT).
The PPT combines the strengths and resources of Ontario’s poultry industry, the provincial government through OMAFRA and the university itself. Only five people, including Sharif, are a part of that team. The others are Gregoy Bedecarrats, Michele Guerin, Csaba Varga and Al Dam. Sharif says the PHRN is a bigger group who can collaborate and co-operate effectively and efficiently, and while the PPT has similar goals, it does have limited scope and mandate, given the narrower expertise.
“PPT will not necessarily phase out. At the time it was formed, it was an important initiative. The PHRN will envelope the PPT and I see it as a very well cemented nucleus to the larger group.”
Right now, Sharif says that as the co-ordinator, he is spearheading the PHRN, but that doesn’t mean that his research priorities are overshadowed.
“As a part of our vision, there is the provision for funds for an NSERC (National Sciences and Engineering Research Council) industrial chair in poultry health,” says Sharif. “And if that does take place, then the incumbent would take over direction of the whole initiative. They would then have a lot of administrative responsibility and would likely be relieved of some other duties in order to focus more attention to the PHRN. We will likely talk to the four marketing boards about helping to fund this as well.”
Sharif says the PHRN also helps to fulfil the expectations of the new Animal Health Lab and Pathobiology building where his office is situated.
“We’re sitting in a 2 ½-year-old building that was built with $70-75 million of taxpayers’ money – money that came to the university based on the premise that we would be enhancing our diagnostic capacities and animal health research related capacities. I don’t think that there is another facility like this anywhere in North America. We have the critical mass. We have the momentum and the PHRN will help us to maintain that forward impetus.”
In A NUTSHELL
PHRN members have expertise in:
- diseases of poultry (diagnostics, mechanisms, prevention, treatment, modelling and epidemiology)
- poultry production, nutrition, welfare and economics
- public health and environmental impacts of poultry production
- Dr. Agnes Agunos, Public Health Agency of Canada
- Dr. John Barta, Pathobiology
- Dr. Gregoy Bedecarrats, Animal and Poultry Science
- Dr. Andrew Bendall, Molecular and Cellular Biology
- Dr. Patrick Boerlin, Pathobiology
- Dr. Martina Brash, Pathobiology
- Dr. Hugh Cai, Animal Health Laboratory
- Dr. Sylvain Charlebois, Management and Economics
- Mr. Al Dam, Ontario Ministry of Agriculture and Food
- Dr. Rob Deardon, Mathematics and Statistics
- Dr. Joshua Gong, Agriculture and Agri-Food Canada
- Dr. Michele Guerin, Population Medicine
- Dr. Mansel Griffiths, Food Science
- Dr. Alice Hovorka, Geography
- Dr. Robert Jacobs, Pathobiology
- Dr. Gordon Kirby, Biomedical Science
- Dr. Steven Leeson, Animal and Poultry Science
- Dr. Emily Martin, Animal Health Laboratory
- Dr. Eva Nagy, Pathobiology
- Mr. Tim Nelson, Livestock Research Innovation Corporation
- Dr. Davor Ojkic, Animal Health Laboratory
- Dr. John Prescott, Pathobiology
- Mr. Keith Robbins, PIC Executive Director
- Dr. Bruce Roberts, Canadian Poultry Research Council
- Dr. Jan Sargeant, Centre for Public Health and Zoonoses
- Dr. Shayan Sharif, Pathobiology
- Dr. Durda Slavic, Animal Health Laboratory
- Dr. Dale Smith, Pathobiology
- Dr. Trevor Smith, Animal and Poultry Science
- Dr. Deborah Stacey, Computer Science
- Dr. James Squires, Animal and Poultry Science
- Dr. Patricia Turner, Pathobiology
- Dr. Bill Van Heyst, School of Engineering
- Dr. Csaba Varga, OMAFRA
- Dr. Qi Wang, Agriculture & Agri-Food Canada
- Dr. Keith Warriner, Food Science
- Dr. Tina Widowski, Animal and Poultry Science
By 1957 the farm had incorporated as Shantz Turkeys Ltd. In 1958, Earl Habel started his own growing business, leaving Milo, his brother Ross and their father, Irvine, running the family operation. In 1966, Ralston Purina purchased the turkey breeding, growing and processing enterprise that by then consisted of three companies: Three Star Farms, Shantz Processing and Shantz Hatchery.
Hybrid Turkeys was a name that emerged in 1970 when the Shantz brothers bought back the breeding and growing enterprises. Ralston Purina retained the processing part of that turkey business which had been trading as Checkerboard Farms.
Ross Shantz, now 74, recalls the early days of the business, before further processing was introduced.
“Hybrid Turkeys entered into primary breeding and commercial growing of broiler type turkeys, as it was known at that time, seeing a consumer need when a local processor saw a market for year-round production of a five- to ten-pound table-ready whole bird.”
They needed to build a new turkey, but the genetics they needed for a smaller white bird with superior conformation that could be produced year-round were not available at that time.
Over the next 20 years, Hybrid Turkeys grew to be among the top three breeding companies in the world.
In 1981, Hybrid was sold to Euribrid, but the familiar Hybrid name continued. By the late 1980s Hybrid had become a major global player in turkey genetics with farms in Brazil and Hungary. Ross Shantz remained as president until 1986 and served on the board of directors until 1991.
Milo Shantz reached out beyond the turkey industry to actively promote the business community in St. Jacobs, Ont. He was recognized by Wilfrid Laurier University with an honorary doctorate of laws before he passed away in 2009.
In 2007 Hendrix Genetics acquired the animal breeding division of Euribrid, from Nutreco BV, including its related Animal Breeding Research Centre. Today the turkey breeding division is formally known as Hybrid Turkeys, A Hendrix Genetics Company. To most people though, it’s still just Hybrid Turkeys.
In an address to employees at a 60th anniversary celebration held in June 2013, Dave Libertini, managing director of Hybrid Turkeys, predicted that the company’s future will be similar to the past, and will involve following the same strategy of listening to its customers and the market.
“As a survivor and with 60 years of wisdom, we also intend to look for new ways to deliver what the market wants and we will also look to influence the turkey sector so that it can grow and we can all prosper. The turkey business needs leaders and we think we can offer leadership.”
Ross Shantz also believes the secret of the success of Hybrid Turkeys over the last 60 years was listening to consumer market trends, as well as the needs of the company’s direct customers. He gratefully acknowledges the dedicated employees and consulting people they had worked with over the years.
“It is very humbling to see how an idea 60 years ago has turned into a major contributor to the poultry industry in the 21st century,” says Shantz. “Thanks, Hendrix Genetics and Hybrid employees for keeping the dream alive.”
The term “cluster” is used to describe an approach to science that encourages researchers to work together to reach common goals. Specifically, the Poultry Science Cluster was formed to address a number of research goals identified by the industry and the research within that spanned the “innovation continuum” from basic discovery to practical application. It encompassed 10 core activities involving 21 principal scientists at seven university and government research institutions across the country.
This research contributed to training and professional development of over 40 students, postdoctoral fellows and visiting scientists. Technical information resulting from this research has been shared with the research community through peer-reviewed publications and scientific meetings, and practical information has been shared with industry stakeholders. A number of patent applications and invention disclosures are a direct result of activities within the Cluster.
Here are a few highlights of the results from this work:
- A new understanding of the biology of C. perfringens, a bacterium associated with necrotic enteritis (NE) in poultry. In order to cause NE, a C. perfringens, strain must have a specific genetic makeup that includes certain genes in its chromosomes and others found on plasmids that can be passed from one bacterium to another. Strains of C. perfringens that have acquired the right set of genes have a competitive advantage in the gut and, when conditions are right, are primed to cause disease.
- Progress towards an improved vaccine against Salmonella enteritidis, the design and delivery of which is hoped to simultaneously reduce colonization in the gut of laying hens and prevent spreading infection throughout a flock and potentially on to consumers.
- Demonstration that plant-based essential oils can be used to fight bacterial infections in poultry. Research has shown that encapsulated oils were able to protect birds from NE just as well as dietary antibiotics.
- A new understanding of how avian influenza (AI) virus adapts to and causes disease in modern poultry, including identification of a genetic determinant that “switches” AI virus from low to high pathogenicity.
- Demonstration that airborne transmission could play a role in the spread of AI infection, and that only a very small amount of virus is needed to transmit the disease by indirect contact.
- New information on the bird’s immune reaction to AI infection.
- A prototype virosome-based vaccine that elicits broad immune responses thought to be necessary for adequate protection from AI infection.
- Demonstration that specific compounds (adjuvants) can be combined with the virosome vaccine to further improve immune responses.
- Development of a vaccine vector system (based on a virulent fowl adenovirus) that can be engineered to carry genes coding for specific antigens, and demonstration that it can be used elicit appropriate immune responses upon in ovo (in the egg) injection.
- Progress towards development of a turkey adenovirus-based vector system.
- Development of a DNA-based vaccine that, using a specific administration route, can protect poultry from a highly pathogenic AI virus.
- Demonstration that inclusion of a vitamin D precursor (HyD) in turkey diets, particularly early in life, has beneficial effects on meat yield and early immune function. The study suggests that industry-recommended HyD levels can be reduced by as much as 50 per cent after six weeks of age without loss of benefit, thereby reducing production costs.
- Confirmation that diets containing fibre supplements and/or appetite suppressants may be a viable solution to prevent chronic hunger in feed-restricted broiler breeders.
- Demonstration that toe trimming represents a potential welfare improvement for female turkeys, but the practice may not be beneficial for males.
While the Cluster is officially complete, research projects related to many of its initiatives are ongoing and moving to “next steps.” We’ll keep you posted on future progress.
Aug. 19, 2013 - Researchers at the University of East Anglia (UEA) have identified a rapid response which could help halt infectious diseases such as bird flu, swine flu and SARS before they take hold.
Focusing on the avian flu virus strain H5N1, research published in the journal PLOS ONE identifies key stages in the poultry trade chain which lead to its transmission to other birds, animals and humans.
High risk times for the disease to spread include during transportation, slaughter, preparation and consumption. It is hoped that the findings and recommendations will help stop the spread of other infectious diseases.
The H5N1 avian flu strain has been responsible for the deaths of millions of poultry, as well as 375 confirmed human deaths. Areas of Southeast Asia have been hardest hit with more than 2,500 reported outbreaks among domestic poultry in Vietnam alone. The disease has also spread rapidly from Southeast Asia into Europe. However the way that the virus transmits from poultry to humans has been poorly understood.
The UEA research team adopted a system widely used in the food production industry, known as Hazard Analysis of Critical Control Points (HACCP), and investigated whether it could be used as a rapid response to emerging outbreaks.
They investigated Vietnam’s poultry trade system and identified four key stages within the poultry trade chain which pose high risks for the transmission of HPAI viruses in human and poultry populations:
- Contact within poultry flocks which act as viral ‘mixing pots’. Examples include at markets which act as huge reservoirs for the virus, at bird vaccination centres, and at cock fighting contests.
- Transportation and sale of poultry and eggs.
- Purchase and slaughter of poultry from markets.
- Preparation of poultry for consumption – particularly in unhygienic conditions and when meat is raw or undercooked.
The research was led by Dr Diana Bell and Dr Kelly Edmunds from UEA’s school of Biological Sciences.
Dr Bell said: “Since 1980 an average of one new infectious disease emerges in humans every eight months – representing a substantial global threat to human health.
“Diseases which originate in birds and mammals such as SARS and bird flu represent 60 per cent of outbreaks. As well as representing a significant global health threat, they also create a burden to public health systems and the global economy.
“We identified poultry transportation, slaughter, preparation and consumption as critical control points in response to HPAI H5N1 outbreaks in Vietnam.”
Dr Edmunds added: “We also showed that adopting the Hazard Analysis of Critical Control Points (HACCP) system, which is already used in the food production industry, could work very effectively as a precursor to more time-consuming quantitative data collection and biomedical testing.”
The research was conducted as part of a three year interdisciplinary study of the impact of H5N1 on mechanisms of transmission, local livelihoods and food security. It was funded by the Economic and Social Research Council (ESRC) and the Natural Environment Research Council (NERC).
‘Hazard Analysis of Critical Control Points Assessment as a Tool to Respond to Emerging Infectious Disease Outbreaks’ by Kelly L. Edmunds, Paul R. Hunter, Roger Few and Diana J.Bell, was published in the journal PLOS ONE on August 14, 2013.
Until September 9, 2013, special early bird registration rates are available. For the complete list, see below.
|Registration Type||Early Bird Rate (Until Sept. 9)||Regular Rate (After Sept. 9)|
|Discounted Sponsor Registration||$350||$400|
|Student Registration Package||$200||$250|
|Guest Meal Package||$200||$250|
To register for the PSIW, please click here. For the complete program, as well as nomination forms for the Poultry Service Industry Award and sponsorship opportunities, please visit http://poultryworkshop.com/index.php?page=agenda.
Aug. 14, 2013 - A serology study in a Chinese province hit hardest by novel H7N9 influenza found evidence of asymptomatic or mild infections in poultry workers, further strengthening suspicions that poultry are the source of the outbreak.
The study focused on members of the general public, poultry workers, and patients with lab-confirmed H7N9 infections in Zhejiang province, which has recorded 45 cases during the outbreak thus far. The Chinese researchers published their findings in the Aug 9 early online edition of the Journal of Infectious Diseases. The full article can be purchased here.
They collected and analyzed serum samples, along with epidemiologic data, from 1,129 people from three Zhejiang cities in the province that had human H7N9 cases. The group also collected serum samples and nasal swabs from 396 people who had occupational exposure to poultry in districts where human cases had been found.
Among poultry workers, 6.3% had antibodies against the new H7N9 virus, based on hemagglutinin inhibition (HI) assay titers of 80 or greater. In contrast, the investigators found no evidence of antibodies in the general population.
No viral evidence was found in the workers' nasal swab samples.
The results weren't surprising, because a study more than a decade ago in poultry workers showed a similar seroprevalence to avian H7 subtypes, according to the report.
"Our data support the conclusion that H7N9 virus or a closely related virus is circulating in live poultry markets and that infected poultry is the principal sources for human infections," they wrote.
Serum findings in poultry workers also hint that subclinical infections occur. However, the researchers noted that an earlier study using blood samples collected from poultry workers in four provinces found no evidence of H7N9 exposure, suggesting that the workers in Zhejiang only recently developed the antibodies against the virus.
The team said it's possible that the H7N9 antibodies they detected in the poultry workers might reflect exposure to other similar H7 avian influenza viruses, including an H7N3 virus that affected ducks in the regions.
The lack of findings in the general population could signify that cross-species transmissions are recent and sporadic events, and the ability of H7N9 to spread between humans is so far limited, the team concluded.
China reports another H7N9 death
Meanwhile, a 61-year-old patient recently announced as Hebei province's first case died today, raising the number of deaths from the disease to 44, according to Xinhua, China's state news agency. The patient's illness was first announced in the middle of July.
Though the number of infections have tailed off in China, the country continues to report sporadic cases, the latest one a 51-year-old poultry worker from Guangdong province whose suspected infection was first reported on Aug 9.
China's National Health and Family Planning Commission has confirmed the woman's infection, according to a statement yesterday from the World Health Organization (WHO). Her illness raises the outbreak's total to 135 cases.
The woman got sick on Jul 27 and was hospitalized the following day. She is in critical condition.
So far there is no sign of sustained human-to-human transmission, the WHO said. At this point four patients sickened in the outbreak are still hospitalized, and 87 have been discharged, the agency added.
Research published in the British Medical Journal (BMJ) analyzing a family cluster of cases of H7N9 infection in eastern China found it was very likely the virus "transmitted directly from the index patient (a 60-year-old man) to his daughter."
Experts commenting on the research said while it did not necessarily mean H7N9 is any closer to becoming the next flu pandemic, "it does provide a timely reminder of the need to remain extremely vigilant."
"The threat posed by H7N9 has by no means passed," James Rudge and Richard Coker of the London School of Hygiene and Tropical Medicine said in a commentary in the same journal.
The scientists who led the study stressed, however, that the virus has not yet gained the ability to transmit from person to person efficiently - meaning the risk is very low that it could cause a human pandemic in its current form.
The new bird flu virus, which was unknown in humans until February, has so far infected at least 133 people in China and Taiwan, killing 43 of them, according to the latest World Health Organization (WHO) data.
Most cases have been in people who had visited live poultry markets or had close contact with live poultry in seven to 10 days before falling ill.
The BMJ study, lead by Chang-jun Bao at the Jiangsu Province Centre for Disease Control and Prevention, analyzed a family cluster of two H7N9 patients -- a father and daughter -- in eastern China in March 2013.
The first "index" patient, a 60-year-old man, regularly went to a live poultry market and fell ill five to six days after his last exposure to poultry.
He was admitted to hospital on March 11. When his symptoms became worse, he was transferred to an intensive care unit (ICU) on March 15 but died of multi-organ failure May 4, the study reported.
The second patient, his healthy 32-year-old daughter, had no known exposure to live poultry but provided direct bedside care for her father in the hospital before he went to intensive care.
She developed symptoms six days after her last contact with her father and went into hospital on March 24. She was moved to the ICU on March 28 and died of multi-organ failure on April 24.
Strains of the virus isolated from samples taken from each patient were "almost genetically identical" -- a strong suggestion that the virus was transmitted directly from father to daughter, the researchers said.
"To our best knowledge, this is the first report of probable transmissibility of the novel virus person-to-person with detailed epidemiological, clinical and virological data," they wrote.
Peter Horby of the Oxford University clinical research unit in Hanoi, Vietnam, who was not involved in this research, said the study raised the level of concern about H7N9 and reinforced the need for intensive surveillance.
Aug. 7, 2013 - The first report of probable person to person transmission of the new avian influenza A (H7N9) virus in Eastern China has been published on bmj.com. The findings provide the strongest evidence yet of H7N9 transmission between humans, but the authors stress that its ability to transmit itself is "limited and non-sustainable."
The Avian influenza A (H7N9) virus was recently identified in Eastern China, and as of June 30, 2013, 133 cases have been reported, resulting in 43 deaths.
Most cases appear to have visited live poultry markets or had close contact with live poultry seven to 10 days before illness onset. Currently no definite evidence indicates sustained human-to-human transmission of the H7N9 virus, but the study reports a family cluster of two patients (father and daughter) with H7N9 virus infection in Eastern China in March 2013.
The first (index) patient – a 60 year old man – regularly visited a live poultry market and became ill five to six days after his last exposure to poultry. He was admitted to hospital on March 11.
When his symptoms became worse, he was transferred to the hospital's intensive care unit (ICU) on March 15. He was transferred to another ICU on March 18 and died of multi-organ failure on May 4th.
The second patient, his healthy 32 year old daughter, had no known exposure to live poultry before becoming sick. However, she provided direct and unprotected bedside care for her father in the hospital before his admission to intensive care.
She developed symptoms six days after her last contact with her father and was admitted to hospital on March 24. She was transferred to the ICU on March 28 and died of multi-organ failure on April 24.
Two almost genetically identical virus strains were isolated from each patient, suggesting transmission from father to daughter.
Forty-three close contacts of both cases were interviewed by public health officials and tested for influenza virus. Of these, one (a son in law who helped care for the father) had mild illness, but all contacts tested negative for H7N9 infection.
Environmental samples from poultry cages, water at two local poultry markets, and swans from the residential area, were also tested. One strain was isolated but was genetically different to the two strains isolated from the patients.
The researchers acknowledge some study limitations, but say that the most likely explanation for this family cluster of two cases with H7N9 infection is that the virus "transmitted directly from the index patient to his daughter." But they stress that "the virus has not gained the ability to transmit itself sustained from person to person efficiently."
They believe that the most likely source of infection for the index case was the live poultry market, and conclude: "To our best knowledge, this is the first report of probable transmissibility of the novel virus person to person with detailed epidemiological, clinical, and virological data. Our findings reinforce that the novel virus possesses the potential for pandemic spread."
So does this imply that H7N9 has come one step closer towards adapting fully to humans, ask James Rudge and Richard Coker from the London School of Hygiene and Tropical Medicine, based in Bangkok, in an accompanying editorial?
Probably not, they say. Limited transmission between humans "is not surprising, and does not necessarily indicate that the virus is on course to develop sustained transmission among humans."
Nevertheless, they point to several traits of H7N9 are of particular concern, and conclude that, while this study might not suggest that H7N9 is any closer to delivering the next pandemic, "it does provide a timely reminder of the need to remain extremely vigilant: the threat posed by H7N9 has by no means passed."
The authors also summarise their findings in a video abstract. Dr Zhou says that the reason for carrying out this study was because there was "no definite evidence to show that the novel virus can transmit person-to-person," plus she and her co-authors wanted to find out whether the novel avian influenza virus possesses the capability to transmit person-to-person. She concludes that "the infection of the daughter is likely to have resulted from her father during unprotected exposure" and suggest that the virus possesses the ability to transmit person-to-person in this cluster. She does add however that the infection was "limited and non-sustainable as there is no outbreak following the two cases."
For more information on the research, please see the video abstract provided by BMJ.com:
Jul. 30, 2013 - As in many other jurisdictions, Canadian governments, both federal and provincial, played a part in poultry breeding in the past 100 years. In Canada, the federal government had a very strong research program in poultry genetics from the 1950s until the 1990s. In addition, several universities – notably Guelph and Saskatchewan – had significant programs of genetics research and teaching that helped the industry develop.
The Canada Department of Agriculture (as Agriculture and Agri-Food Canada was then known) established a Record of Performance (ROP) system that enabled breeders to have independently audited records of progeny tested cocks, whose progeny would sustain increased prices for hatching eggs and chicks. In addition, laying tests were established in most provinces to test small groups of hens submitted at point of lay, to independent testing stations. However, by the middle of the last century, it became obvious that the results of these tests depended at least as much on the skill of the breeder in growing and selecting the birds as on their breeding value or genetic potential. In addition, sample sizes were quite small.
The Random Sample Test became the accepted method of comparing stocks from different breeders. The tests consisted of obtaining samples of hatching eggs from the breeders to hatch at least 100 pullets (in some cases more), which were grown under standard conditions. They were housed in standard cages, with a randomly distributed, replicated pattern, and the identity of each group was unknown to those looking after the birds. The last surviving Canadian Random Sample Test, in Ottawa, was shut down in 1990.
Basic studies in poultry genetics were a large part of the federal government's wide-ranging research program. The outcome was of interest not only to commercial poultry breeders, but also to breeders of other farm animals. Dr. Robb Gowe established the major poultry genetics program in the early 1960s, and although mainly based in Ottawa, the program (in its early stages) had replicates of the selected populations in several federal stations across the country. The primary goal of the program was to investigate broad-based populations (derived from commercial White Leghorn hybrids) for commercially important traits like egg numbers, egg weight, egg quality, liveability, etc. A unique aspect of the research was that unselected control populations were maintained so as to separate the effects of genetic selection from those of uncontrolled changes in the environment. Although these selected lines eventually became highly productive, they were, as far as is known, never used in a commercial environment.
Another federal government program specifically designed to provide stock to commercial breeders, operated for a few years in the 1960-70s under the guidance of Sterling Munroe. According to Donald Shaver, this was instituted to provide a Canadian alternative to his "monopoly" on the supply of parent stock! Fisher Poultry Farms, in Ontario, used the stock for a few years.
Poultry Health Programs
Provincial governments at the time were primarily involved in developing poultry health control measures. The diseases of concern were those unwittingly passed from parents to commercial offspring.
In the early days of the rise of commercial hatcheries, Pullorum disease (also known as bacillary white diarrhoea, caused by the bacterium Salmonella pullorum) was a constant threat. The disease was characterized by adult carriers, which showed no symptoms, passing the bacteria through the hatching eggs to baby chicks, which suffered very high mortality. Fortunately, a rapid blood test was developed that could detect the carriers. Most provincial governments provided testing services for parent flocks, and any carriers were removed from the breeding flocks. As a result, Pullorum disease is rarely seen today.
Individual breeders in the latter part of the 100-year period also eradicated, by various means, other Salmonella species, and several strains of Mycoplasma. These actions were mainly voluntary, although some assistance from governments was available.
As a result of these programs, breeders being shipped today are guaranteed to be free of Salmonella pullorum, Mycoplasma gallisepticum, and a variety of other pathogens specific to individual breeders and poultry types.
The first off the bat was for EFO, committing $1 million toward developing the antidepressant drug, Rellidep™, named after Ron Ellis, who was a star player with the Toronto Maple Leafs and Team Canada in 1972. The research is being done by United Paragon Associates Inc., a privately owned, Ontario-based company.
If this exciting project is successful, the impact could be felt around the world, much like another great Canadian medical discovery – insulin. Lianne Appleby wrote an excellent story about Rellidep in the June edition of Canadian Poultry and if you haven’t read it, you really should.
Ron Ellis played for the Leafs from 1963 to 1981. I was such a huge fan of Ellis, I wrote him a letter when the Leafs let him go. He responded with a handwritten note thanking me for my comments. He is a class act and I was shocked when I later found out he had been suffering from serious depression for many years.
Like thousands of other Canadians, Ellis had managed to hide his depression. To his credit, he later decided to use his fame, name and personal story to raise public awareness about this debilitating and often life-threatening medical condition. Today, he is a leader and the face of Rellidep.
Ontario’s egg farmers deserve a standing ovation for stepping up to the plate to help champion this important medical research. I wish the Rellidep project and Ron Ellis all the success in the world.
As for Team Eggs’ second home run, anyone who reads Canadian Poultry magazine knows that despite relentless media attacks, supply management has the support of the federal government, all provincial governments and the vast majority of individual MPs and MPPs – but what about municipal governments? Why not find out what those people think, too?
Well, that is exactly what Egg Farmers of Canada (EFC) did.
The EFC recently commissioned Ipsos Reid to conduct a survey called “Canada’s Mayors and Reeves on Supply Management.” The survey included 124 intensive interviews with mayors, deputy mayors and reeves across Canada. It included many of Canada’s largest cities – meaning that the survey wasn’t limited to rural areas. The jurisdictions included represent 25 per cent of Canada’s population, and there were interesting results.
For example, there was an overwhelming understanding of the need to keep local dairy and poultry farms healthy, realizing the important role farming plays in the local economy. Almost 90 per cent of those surveyed support supply management, with 40 per cent being very supportive. Eighty per cent agreed that supply management is important to the survival of farmers and communities, with almost 50 per cent agreeing strongly.
The survey also revealed that 74 per cent of those surveyed agreed there is no guarantee that getting rid of supply management would lower dairy, egg and poultry prices for consumers. And that result alone was worth the price of admission.
EFC has concluded there is an opportunity for farmers and stakeholders to expand education efforts to dispel myths and falsehoods in an effort to increase further dialogue at the local (municipal) level.
I couldn’t agree more, because nobody is closer to local issues than elected municipal representatives. I think EFC’s decision to commission this survey was brilliant and the timing was perfect. Despite the hundreds of anti-supply management articles and columns that have been published in major daily newspapers or posted online, and the heavy criticism we have all heard and seen on radio and TV, it is important to remember that supply management is not an issue for most Canadians.
In fact, many people (of those who are even aware of it) support supply management. The Ipsos Reid survey has reminded us of that.
The Mayors and Reeves survey and Rellidep are both home runs in my book. Well done, Team Eggs.
Jun. 28, 2013, Ottawa, ON - Genome Canada, the Canadian Food Inspection Agency (CFIA), and Alberta Innovates Bio Solutions have partnered to support a $1.4 million project that will help protect consumers from Listeriosis, a serious foodborne illness caused by Listeria bacteria.
The project, led by Dr. Linda Chui of the University of Alberta, will sequence and map the genomes of different Listeria strains to identify those that are likely to be most harmful to human health, as well as those most likely to survive in food processing facilities.
Through this research, a database of Listeria genome sequences will be developed and genetic markers identified. These markers will be used to rapidly spot harmful Listeria strains in foods and food processing facilities.
"Genomics research such as this is equipping us with new, effective ways to combat threats to food safety. The impact this research will have on averting potential outbreaks and the consequences for Canadian families and industry is tremendous," said Pierre Meulien, President and CEO of Genome Canada.
"Ensuring the safety of food products is critical to public health and the competitiveness of our agri-food and agriculture industries," said Dr. Stan Blade, Chief Executive Officer of Alberta Innovates Bio Solutions. "New Listeria detection tests that produce results quickly will allow food producers and regulators to act swiftly and provides assurance of an even higher level of food safety for Canadians," he added.
Dr. Chui's 18-month research project is supported through an investment of $250,000 each from Genome Canada (via Genome Alberta) and the CFIA, and $100,000 from Alberta Innovates Bio Solutions. This investment is also being leveraged through co-funding from federal, provincial, academic and industry partners, including Maple Leaf Foods, increasing the total investment to $1.4 million.
"The strength of our project is in the world-class expertise of the research team and the support of many distinguished organizations from across Canada," said Dr. Chui. "The different researchers on the team bring leading-edge expertise in many areas including food sample preparation, assays development, state-of-the art capacity in bioinformatics and genomics, pathogen detection and outbreak response."
Aloapur®, a bio based animal feed solution for the improvement of the general health of animals, has been developed and patented by Purac. Aloapur is based on Lactylates and has been developed for the first time in animal nutrition and has demonstrated to significantly improve growth and feed conversion in poultry and turkey production in particular in suboptimal conditions. The efficacy of Aloapur has been extensively tested and demonstrated in both scientific research as well as actual production farms by Purac and Cargill.
Commercial production will start in July in a newly built production facility at the Purac site in Gorinchem, the Netherlands.
Cargill brings its animal nutrition expertise and global footprint to the partnership. Cargill’s Provimi business will develop the application and offer Aloapur to customers to help them improve animal health and nutrition. Cargill Animal Nutrition is committed to selecting and developing innovative solutions that can significantly improve animal nutrition.
Marco Bootz, Vice President Chemical & Pharma at Purac, comments: "CSM is developing into a leading provider of bio-based ingredients and solutions. Our collaboration with Cargill is fully in line with our strategy to develop commercially attractive bio-based alternatives using renewable and sustainable resources. This new technology, Aloapur®, for animal health is based on our core competence in lactic acid derivatives and emulsifiers. We believe that this technology has the potential to significantly reduce the usage of low dosage antibiotics as growth promoters in animal feed, without negatively impacting production. Cargill, the world leader in animal feed, will market Aloapur®, opening up a world of opportunities."
“The use of lactylates in poultry feeds is an exciting new concept in animal nutrition,” said Scott Ainslie, Vice President of Strategic Marketing and Technology at Cargill Animal Nutrition. “This technology offers a promising, innovative nutritional solution to improve broiler and turkey health and growth in suboptimal conditions; and Cargill’s Provimi business is perfectly positioned to help bring this solution to the marketplace.”
It was 1873 when Robert Oettel, a German poultry fancier, first described “feather pulling” or “feather eating.” Today, studies in the United Kingdom indicate that 78 per cent of hens engage in severe feather pecking, with similar numbers in the European Union. Bring those numbers to Canada, where there are about 22.5 million hens, and that means the behaviour could affect up to 17.6 million Canadian birds.
The answer to why hens feather-peck has eluded researchers for 140 years. “It’s an old problem,” says Austrian veterinarian Dr. Alexandra Harlander, one of the world’s experts on feather pecking in laying hens, who has recently joined the poultry welfare faculty at the University of Guelph.
Harlander posed a question at a recent lecture in Guelph hosted by the Campbell Centre for the Study of Animal Welfare: Is feather pecking redirected behaviour from food pecking, ground pecking or dust bathing? As she explains, it’s generally accepted as a multi-factorial process, involving genetics, management and nutrition.
So far, detective work has explored many facets of feather pecking, from natural behaviours to diets to digestive differences in the birds themselves. However, Harlander is convinced that feather pecking is redirected foraging behaviour, not redirected dust-bathing behaviour.
She describes foraging as having two components: seeking and consumption. It’s possible that feather pecking is part of exploration. Hens without some sort of floor substrate, such as wood shavings, will display an increase in feather pecking behaviour. Is it possible that birds may misperceive feathers as a foraging substrate?
It is known that birds don’t mind working to find food, but do they work as hard for feathered feeds?
|Feather pecking is an old problem, but a very important one.
Harlander references her study where hens with high and low feather-pecking (HFP and LFP) tendencies were offered food pellets, loose feathers and fixed feathers as a food source. The results showed that both groups of birds ate the same amount, but the HFP hens preferred a higher-feather diet (see photo above).
But would HFP and LFP birds prefer feathers over shavings?
Birds were then individually presented with a bowl of wood shavings, a bowl of feathers, an empty dish and a bowl of mash. The HFP birds voted for the feathers.
This raised another question: How hard would birds work to get wood shavings or feathers? Birds were asked to peck a key or press a lever with food, wood shavings or feathers as a reward (known as operant conditioning). The HFP and LFP lines didn’t differ when food or shavings were the reward, but when feathers were rewarded, the HFP birds became highly motivated.
What is it about feathers that make them attractive? Harlander described the process of consumption as follows: we see the food, touch it, smell it, taste it and decide to either swallow it or spit it out.
But for feathers, the distinction is more difficult. Feather colour doesn’t seem to make a difference; neither does feather placement. While some flocks start in pecking in one area, others concentrate on other areas and we don’t know why – research has shown no area preference so far.
Birds have shown a preference, however, for shorter feathers, choosing two- or four-centimetre feathers over six- or eight-centimetre feathers. This shows that physical characteristics are important, says Harlander. Birds also seem to prefer the tip or middle part of the feather and avoid the calamus, the stiff part.
It is possible that chemosensory cues have an influence as well. Birds preferred washed feathers to unwashed feathers, and they loved feathers soaked in garlic but avoided bitter quinine feathers.
With the quinine feathers, both groups of birds showed a reduction in severe feather-pecking bouts, but returned to their old behaviour after three weeks.
If HFP birds are so highly motivated to feather-peck, why not mix feathers into the food? Harlander says that making feathers available in the HFP feed will substitute the specific appetite for feathers and therefore actually reduce pecking activity compared with birds provided with normal feed or birds given feed containing insoluble cellulose instead of feathers.
This further led Harlander’s team to wonder if the fibre source or concentration would make a difference. When birds were fed isocaloric (similar caloric content) feeds of similar particle size, those with five per cent chopped feathers and five per cent cellulose in the diet had the same number of severe feather-pecking bouts, while providing a diet of 10 per cent feathers reduced feather pecking significantly and improved plumage condition.
However, the mechanism by which fibre reduces feather pecking remains unknown.
Harlander hypothesizes that feathers, as non-nutritive substances, may act the same as insoluble fibre, by speeding up feed passage time. Studies have shown this to be the case, with feed passage time being fastest with high-feather diets.
The physical structure of the feathers increased the grinding activity of the gizzard, affecting peristaltic movement of the gut. Ingested feathers increased the speed of feed passage, but wood shavings did not.
In summary, both HFP and LFP birds explore at similar levels, but because the HFP birds showed a specific, strong appetite for feathers, substituting litter substrate was not effective. As well, feather ingestion increases the rate of food passage and can affect gut micro biota.
Feather pecking seems to be a multi-factorial issue that affects both organic and conventional commercial operations, resulting in mortality and loss of productivity. Group housing may actually encourage feather pecking, with birds picking up the behaviour by watching and imitating other birds.
Birds with access to an outdoor run (free-range birds with access to outside light) do not have a lower or higher level of feather pecking than birds kept inside their entire lives. Light intensity in general can influence feather pecking, but the behaviour has nothing to do with indoor or outdoor housing.
While her research at Guelph will continue to explore the feather-pecking mystery, Harlander suggests that producers experiment with genetic selection for feather-pecking propensity or spraying birds with a bitter-tasting substance if feather pecking is a problem.
Eggs, it can be said, have had their fair share of the media spotlight. There was a time when it seemed they were to be blamed, solely, for high cholesterol and, (if we really want to exaggerate), for the heart attacks of many an unsuspecting consumer. Now, as with many dietary staples, it’s generally accepted that when consumed in moderation, eggs can be part of a healthy diet.
Most readers will be thinking, “well, we knew that all along, it’s common sense”. And, like many, other examples of bad media, the only thing to do was to ride out the unwanted publicity storm.
What do you do when the reverse is true, though – when ground-breaking research shows that eggs may be the answer to one of the most crippling conditions a person can suffer? Well, if you’re Egg Farmers of Ontario (EFO), you support further work on the subject and view it as a research and development investment.
Thus, on March 26, EFO announced at their annual meeting in Mississauga that they will provide $1 million to United Paragon Associates (UPA), an Ontario-based privately-held pharmaceutical developer, to fund clinical trials for a new antidepressant drug that could help millions of people, worldwide, who suffer from Major Depressive Disorder (MDD).
Cleverly named Rellidep™* (after former hockey great, Ron Ellis, long-time champion in the fight against MDD, and UPA’s Vice-President of Public Relations) it would be an understatement to say that there are high-hopes for Phase 2 of clinical trials.
If any of this sounds familiar, it shouldn’t. EFO has never before supported such work. In fact, when it comes to commodity groups, Ontario’s egg board is probably the only group in Canada currently funding the development of a human health drug. And whether you eat eggs or not, depression is very likely a condition that has affected you or someone very close to you.
According to the Canadian Mental Health Association’s Website, “depression is a term used to describe a long period when a person is sad to the point of feeling worthless, hopeless and helpless. It can be caused by stress, a loss, or a major disappointment, but sometimes, it seems to happen for no particular reason at all – the result of a chemical imbalance in a person’s body.” Statistics Canada’s 2002 Mental Health and Well-being Survey showed that 5.3 per cent of the Canadian population aged 15 years and over had reported symptoms that met the criteria for MDD in the previous 12 months, including 4.8 per cent for major depression and 1 per cent for bipolar disorder.
When EFO was approached by UPA, they were told that the company had found that fertilized eggs could play a key role in alleviating depression. Given the millions of Canadians battling the disorder and the simple “good news story” that could come of it, it was a no-brainer for Ontario’s egg farmers to get behind the work.
“I got introduced to it last fall,” said EFO chair Scott Graham. “Our general manager, Harry Pelissero, had been introduced probably a year previous to that. We’ve signed a letter of intent for a million dollars that we hope is going to be a stimulus to help [UPA] raise another $7.5 million [to undertake] a second clinical trial.”
Graham is hopeful the results will be as favourable as they were in the first trial. Those findings indicated that Rellidep may be more successful in alleviating depression than other drugs currently on the market, while at the same time resulting in fewer and less disruptive side effects.
“Despite recent advances in treatment, there continues to be great unmet need specific to three key areas in the fight against major depressive disorder,” George Yeung, UPA’s president of Research and Development told the audience in Mississauga. “Early phase trials with Rellidep have demonstrated tremendous promise, as it may offer improvements over currently available drug treatments in three areas. Potentially better efficacy, shorter time-to-clinical-benefit and significantly fewer side-effects were observed. We are hoping to see similar results in the next phases of our research.”
At a certain stage of development, Yeung explained, a specific molecule is taken from embryonic stem cells in fertilized eggs through a proprietary and patented process. It then forms the foundation of the antidepressant, Rellidep. While he agrees with Graham that early results were encouraging, he emphasized that the sample set was small.
With a mandate to explore potential uses of eggs and expand the market, this investment seemed like a great fit for EFO, although its $1 million won’t kick in until UPA raises the remaining $7.5 million to go ahead with Phase 2 of the clinical trials. EFO, according to Graham, was also keen to keep the research in Canada (specifically Ontario) by supporting UPA. Besides that, he cited the innovative nature of the research, the fact that it is not food-related and its potential economic impact as draws for EFO to infuse money into the project. Speaking to a small group of reporters after the announcement was made, Graham’s emotions were evident when he talked about the humanitarian implications of the new drug, should it reach the market.
There is, however, much work to be done before the drug gets to that point. Yeung explained that even if the money needed for Phase 2 is procured, it could be years before the drug is at the point where it can be prescribed. And likely, Rellidep would be out-licensed to a larger multinational pharmaceutical company after Phase 2, so there are still a lot of unknowns, he added. It could take longer than six years for Rellidep even to be approved for human use.
For now, the needed $7.5 million to start up the next trial phase is the most crucial factor for UPA to tackle in getting the drug to market. For Ron Ellis, though, that figure dwindles in comparison to the statistics around economic loss related to depression. In reference to published studies, he said, “the economic cost of lost productivity in Ontario due to depression, as measured by short-term and long-term disability days, is estimated to have been $8.8 billion in Ontario in 2000. Costs due to depression are estimated to have been over $2 billion in Ontario in 1998.”
Thus, for Ontario’s 440 egg producers, there is a collective holding of breath to see how this potential great news story ends. Stay tuned.
* Rellidep is a trademarked product.
About United Paragon Associates Inc. (UPA)
Every summer, Canadian poultry farms experience some degree of heat stress. High temperatures (those above 30°C), combined with elevated humidity, can result in reduced feed intake and possibly heat prostration mortality.
During times of heat stress, flock performance and health may be compromised by reduced intake of vitamins and minerals. Thiamin requirements double during heat stress and there is also reduction in the absorption of fat-soluble vitamins A, D and E.1 This is concurrent with increased excretion of minerals such as sodium (Na+) and potassium (K+), which, in turn, negatively affects the heat dissipation capacity and acid-base balance of the bird, resulting in decreased growth performance.
Birds can get rid of excess heat in one of five ways:
- Conduction – Hot birds will try to cool down by touching water pipes or digging into litter to contact a cool floor. In extreme cases, the breast muscle will develop a pale, cooked appearance after the bird sits for prolonged period of time.
- Convection – Moving air over the birds is the most effective way to keep them cool, but if air is not moving quickly enough, heat can build up around their bodies. In severe heat situations, birds can often be found dead along walls where air does not circulate efficiently. These birds usually die from heat prostration, not from lack of oxygen.
- Radiation – Birds will raise their wings to allow heat to radiate from areas where feather cover is poor. Note that many leghorns survive well in cages because of poor feathering and lack of floor litter, which permits maximum radiation.
- Excretion – Defecation is another means by which heat is lost because birds will typically double their intake of water during periods of heat stress and thus excrete more hot urine and water in feces. It is therefore especially important to ensure your barns have an appropriate drinker ratio, clean water filters and well-adjusted pressure regulators to maximize water delivery during warm weather.
- Evaporative Cooling – Evaporation of water takes place on the surface of the skin and from the respiratory tract. In heat stress conditions, the bird will try to maximize heat loss by panting.
Under heat stress conditions, maintaining water and electrolyte balances are important factors affecting the survivability and productivity of the birds – especially when humidity is high.
By panting, the birds could increase their respiratory rate tenfold; this would result in excessive CO2 loss, which would alter the internal acid-base balance of the bird. By altering their own metabolism, the birds would increase the energy spent towards homeostatic regulation rather than processes supporting growth.2
Excessive water can also be lost through panting and higher urine flow, which negatively influences the birds’ capacity to dissipate heat.3 Unfortunately, ions of sodium, potassium and chloride are also lost. This is dangerous because the ions are important in maintaining the internal acid-base balance and cell membrane integrity of the bird. Some research has shown that sodium chloride and potassium chloride, when administered in the water, were able to alleviate the adverse effects of heat stress.4
Gut lining integrity, which will cause interference with the natural absorption of essential vitamins and minerals, is also compromised under heat stress conditions.
In summary, valuable vitamins and electrolytes can be lost with the rapid respiration and increase urine output caused by heat stress and must be replaced. In many cases, the few dollars spent on water medication such as Electrolytes Plus could have a significant effect upon the productivity of poultry and livestock.
- P.R. Ferket; M.A. Qureshi (1992). Performance and immunity of heat-stressed broilers fed vitamin- and electrolyte-supplemented drinking water. Poultry science. 71: 88-97.
- Mongin, P. (1981) Recent advances in dietary cation-anion balance: applications in poultry. Proceedings of the Nutrition Society. 40: 285-294.
- Belay T. and Teeter, R.G. (1993). Broiler Water Balance and Thermobalance During Thermoneutral and High Ambient Temperature Exposure. Poultry Science 72: 116-124.
- Smith, M.O. and Teeter, R.G. (1987). Influence of feed intake and ambient temperature stress on the relative yield of broiler parts. Nutrition Reports International, 35(2): 299-306.
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